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Table 2 Effect of chloroform and ethyl acetate fractions at different concentrations on MDA-MB-231 cell cycle progressiona

From: Potent antitumor property of Allium bakhtiaricum extracts

Concentration (mg/ml)

Sub-G1

G1

S

G2

Chloroform extract

 (0.005)

16.9 ± 1.5

43.87 ± 1.86

33.85 ± 1.45

12.17 ± 1.01

 (0.0025)

14.95 ± 1.95

43.20 ± 3.60

35.63 ± 0.66

13.43 ± 1.2*

 (0.0012)

10.95 ± 0.15

47.90 ± 2.61

30.98 ± 1.51

20.90 ± 0.5****

 Control/Vehicle

12.23 ± 0.89

46.58 ± 0.91

32.85 ± 0.92

9.58 ± 0.57

Ethyl acetate extract

 (0.006)

20.30 ± 0.3*

48.30 ± 1.8

30.87 ± 1.35

9.21 ± 1.15

 (0.003)

7.22 ± 1.01

47.60 ± 3.2

29.7 ± 2.39

14.01 ± 0.63**

 (0.0015)

7.65 ± 1.33

46.83 ± 1.2

28.53 ± 1.73

16.75 ± 0.45***

  1. aThe data presented are the mean ± SE of three independent experiments. *p < 0.05, **p < 0.01,
  2. ***p < 0.001,****p < 0.0001 relative to control-vehicle