Table 2 IC50 concentrations (μg/ml) of HNE in the 2D Alamar Blue assay and 3D Soft Agar assay
From: Preclinical evaluation of safety and potential of black hellebore extracts for cancer treatment
2D Alamar Blue assay | 3D Soft Agar assay | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Cell type | Batch A HNE | Batch B HNE | Mean HNE | SD | Actinomycin-D | Batch A HNE | Batch B HNE | Mean HNE | SD | Actinomycin-D |
Caki-2 | 220 | 430 | 291 | 105 | 5.40 | 140 | 430 | 211 | 145 | 8.79 |
DLD-1 | 210 | 330 | 257 | 61.5 | 1.58 | 170 | 340 | 227 | 35 | 0.99 |
MKN-1 | 170 | 250 | 202 | 90 | 1.02 | 130 | 270 | 176 | 70 | 0.82 |
LN229 | 460 | 680 | 549 | 110 | 1.51 | 440 | 870 | 584 | 215 | 0.31 |
SK-N-SH | 260 | 490 | 340 | 115 | 1.63 | 330 | 490 | 394 | 80 | 1.00 |