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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Preclinical evaluation of safety and potential of black hellebore extracts for cancer treatment

Fig. 4

IC50-DF of HNE and its main steroidal saponins. IC50-dilution factor (DF) (> 1:100) of HNE and its main steroidal saponins hellebosaponin A and D were measured in five tumor cell lines (Caki-2: renal cell carcinoma, DLD-1: colorectal carcinoma, MKN-1: gastric carcinoma, LN 229: glioblastoma, SK-N-SH: neuroblastoma) by means of Alamar Blue and Soft Agar assays. IC50-DF of hellebosaponin D and macranthosid I was under 1:100. These data are not shown in this figure. The IC50-DF of HNE comprised two batches on average

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