Fig. 4
In vitro effects of PCE on key aspects of glucose homeostasis. (a) Glucose uptake in L6 myotubes in the absence or presence of increasing concentrations of PCE. (b) Hep2G cell endogenous glucose production in the absence or presence of increasing concentrations of PCE. (c-d) Concentration-response curve for PCE (
) and Acarbose (
) mediated inhibition of α-glucosidase (c) and α-amalyase enzyme activity (d) in cell-free systems. All data are represented as mean ± SD percent activity relative to untreated controls. We derived IC50 values and fit curves using a non-liner inhibitory concentration-response equation with variable slope in GraphPad Prism 5.0 software