Skip to main content

Table 3 NK-cell activity and cytokine cluster analysis obtained prior to and after treatments from the two groups

From: Immunomodulatory effects of a mycelium extract of Cordyceps (Paecilomyces hepiali; CBG-CS-2): a randomized and double-blind clinical trial

 

Cordyceps mycelium extract group (n = 39)

Placebo group (n = 40)

p-valueb

Baseline

Week 8

p-valuea

Baseline

Week 8

p-valuea

 

NK-cell activity (%)

33.7 ± 17.4

38.8 ± 17.6

0.025*

37.9 ± 18.2

35.5 ± 19.9

0.282

0.019*

IL-1ß (pg/mL)

3.1 ± 1.3

3.1 ± 2.0

0.741

4.0 ± 7.7

2.7 ± 0.7

0.328

0.360

IL-2 (pg/mL)

3.0 ± 0.8

3.0 ± 0.7

0.446

2.9 ± 0.6

3.0 ± 0.5

0.166

0.126

IL-4 (pg/mL)

10.3 ± 2.7

10.2 ± 2.2

0.662

11.0 ± 6.8

10.9 ± 7.8

0.979

0.764

IL-10 (pg/mL)

5.1 ± 4.5

6.1 ± 6.3

0.205

3.8 ± 3.0

4.2 ± 3.0

0.277

0.458

IL-12 (pg/mL)

5.8 ± 6.2

6.0 ± 6.3

0.389

5.1 ± 3.3

5.2 ± 3.3

0.766

0.523

INF-γ (pg/mL)

10.4 ± 5.4

11.4 ± 7.1

0.100

10.0 ± 5.1

10.7 ± 6.7

0.275

0.741

TNF-α (pg/mL)

6.5 ± 1.5

6.8 ± 1.5

0.214

6.2 ± 1.5

6.6 ± 2.0

0.114

0.918

  1. Values are presented as the mean ± SD
  2. *p < 0.05
  3. aAnalyzed by a paired t-test within groups
  4. bAnalyzed by a linear mixed effect model for repeated measurement data between groups