| |
Cordyceps mycelium extract group (n = 39)
|
Placebo group (n = 40)
|
p-valueb
|
|---|
|
Baseline
|
Week 8
|
p-valuea
|
Baseline
|
Week 8
|
p-valuea
| |
|---|
|
NK-cell activity (%)
|
33.7 ± 17.4
|
38.8 ± 17.6
|
0.025*
|
37.9 ± 18.2
|
35.5 ± 19.9
|
0.282
|
0.019*
|
|
IL-1ß (pg/mL)
|
3.1 ± 1.3
|
3.1 ± 2.0
|
0.741
|
4.0 ± 7.7
|
2.7 ± 0.7
|
0.328
|
0.360
|
|
IL-2 (pg/mL)
|
3.0 ± 0.8
|
3.0 ± 0.7
|
0.446
|
2.9 ± 0.6
|
3.0 ± 0.5
|
0.166
|
0.126
|
|
IL-4 (pg/mL)
|
10.3 ± 2.7
|
10.2 ± 2.2
|
0.662
|
11.0 ± 6.8
|
10.9 ± 7.8
|
0.979
|
0.764
|
|
IL-10 (pg/mL)
|
5.1 ± 4.5
|
6.1 ± 6.3
|
0.205
|
3.8 ± 3.0
|
4.2 ± 3.0
|
0.277
|
0.458
|
|
IL-12 (pg/mL)
|
5.8 ± 6.2
|
6.0 ± 6.3
|
0.389
|
5.1 ± 3.3
|
5.2 ± 3.3
|
0.766
|
0.523
|
|
INF-γ (pg/mL)
|
10.4 ± 5.4
|
11.4 ± 7.1
|
0.100
|
10.0 ± 5.1
|
10.7 ± 6.7
|
0.275
|
0.741
|
|
TNF-α (pg/mL)
|
6.5 ± 1.5
|
6.8 ± 1.5
|
0.214
|
6.2 ± 1.5
|
6.6 ± 2.0
|
0.114
|
0.918
|
- Values are presented as the mean ± SD
- *p < 0.05
- aAnalyzed by a paired t-test within groups
- bAnalyzed by a linear mixed effect model for repeated measurement data between groups
