Cordyceps mycelium extract group (n = 39) | Placebo group (n = 40) | p-valueb | |||||
---|---|---|---|---|---|---|---|
Baseline | Week 8 | p-valuea | Baseline | Week 8 | p-valuea | ||
NK-cell activity (%) | 33.7 ± 17.4 | 38.8 ± 17.6 | 0.025* | 37.9 ± 18.2 | 35.5 ± 19.9 | 0.282 | 0.019* |
IL-1ß (pg/mL) | 3.1 ± 1.3 | 3.1 ± 2.0 | 0.741 | 4.0 ± 7.7 | 2.7 ± 0.7 | 0.328 | 0.360 |
IL-2 (pg/mL) | 3.0 ± 0.8 | 3.0 ± 0.7 | 0.446 | 2.9 ± 0.6 | 3.0 ± 0.5 | 0.166 | 0.126 |
IL-4 (pg/mL) | 10.3 ± 2.7 | 10.2 ± 2.2 | 0.662 | 11.0 ± 6.8 | 10.9 ± 7.8 | 0.979 | 0.764 |
IL-10 (pg/mL) | 5.1 ± 4.5 | 6.1 ± 6.3 | 0.205 | 3.8 ± 3.0 | 4.2 ± 3.0 | 0.277 | 0.458 |
IL-12 (pg/mL) | 5.8 ± 6.2 | 6.0 ± 6.3 | 0.389 | 5.1 ± 3.3 | 5.2 ± 3.3 | 0.766 | 0.523 |
INF-γ (pg/mL) | 10.4 ± 5.4 | 11.4 ± 7.1 | 0.100 | 10.0 ± 5.1 | 10.7 ± 6.7 | 0.275 | 0.741 |
TNF-α (pg/mL) | 6.5 ± 1.5 | 6.8 ± 1.5 | 0.214 | 6.2 ± 1.5 | 6.6 ± 2.0 | 0.114 | 0.918 |