|
Plant extract/Fractionate
|
Percentage α-glucosidase inhibition
|
IC 50 (μg/mL)
|
|---|
|
12.5 μg/mL
|
25 μg/mL
|
50 μg/mL
|
100 μg/mL
|
200 μg/mL
|
400 μg/mL
| |
|---|
|
Cornus capitata (Leaves)
|
63.68 ± 1.98a
|
97.81 ± 0.03a
|
98.37 ± 0.12a
|
97.43 ± 0.18a
|
97.18 ± 0.18
|
94.70 ± 0.41
|
12.5
|
|
Hexane Fraction
|
2.78 ± 2.73b
|
16.04 ± 4.78b
|
31.94 ± 5.17b
|
69.07 ± 2.51a
|
98.98 ± 1.22
|
96.52 ± 3.02
|
65.12
|
|
Diethyl ether Fraction
|
8.31 ± 0.87b
|
13.04 ± 2.80b
|
30.98 ± 4.21b
|
52.64 ± 6.11a
|
96.54 ± 0.92
|
95.65 ± 0.65
|
71.85
|
|
Ethyl acetate Fraction
|
14.60 ± 3.07bc
|
18.42 ± 2.65b
|
50.06 ± 0.36bc
|
84.45 ± 2.80a
|
98.55 ± 0.51
|
97.45 ± 1.08
|
50
|
|
n-Butanol Fraction
|
10.57 ± 0.21bc
|
14.93 ± 2.83b
|
26.07 ± 4.53bc
|
78.75 ± 4.63ab
|
98.35 ± 0.24
|
97.75 ± 0.43
|
61.175
|
- Values are mean ± S.E. of three parallel measurements
- Different letters indicate significant differences between same concentrations of Cornus capitata methanolic extract and its fractionates (p < 0.05, Tukeys HSD test, F-ratio- 49.935 (12.5 μg/mL), 55.279 (25 μg/mL), 46.702 (50 μg/mL), 16.690 (100 μg/mL), 1.861 (200 μg/mL), 0.683 (400 μg/mL)
- Cornus capitata methanolic extract (leaves) (4.25% at 1.5 μg/mL; 6% at 3.1 μg/mL and 19% inhibition at 6.25 μg/mL concentration)
