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Table 1 α-glucosidase activity of methanolic extracts of different medicinal plants and Acarbose (standard drug)

From: In vitro evaluation of the α-glucosidase inhibitory potential of methanolic extracts of traditionally used antidiabetic plants

Plant

Percentage α-glucosidase inhibition (%)

IC 50 (μg/mL)

12.5 μg/mL

25 μg/mL

50 μg/mL

100 μg/mL

200 μg/mL

400 μg/mL

 

Acarbose (Standard)

18.83 ± 3.87b

30.18 ± 0.06b

42.43 ± 0.05b

56.31 ± 0.02b

80.10 ± 0.15b

89.40 ± 0.09a

66.07

Cornus capitata (Leaves)

63.68 ± 1.98a

97.81 ± 0.03a

98.37 ± 0.12a

97.43 ± 0.18a

97.18 ± 0.18a

94.70 ± 0.41a

12.5

Clematis grata (Whole plant)

0.32 ± 5.79b

4.83 ± 1.46c

5.05 ± 0.74d

5.65 ± 0.75b

8.72 ± 5.09c

13.25 ± 1.10b

Roylea cinerea (Leaves)

8.66 ± 0.20b

9.87 ± 0.16c

10.50 ± 0.66c

14.62 ± 4.20b

15.31 ± 2.60c

20.09 ± 2.21b

Roylea cinerea (Stem)

5.85 ± 1.50b

6.54 ± 3.04c

7.01 ± 1.23d

8.69 ± 1.87b

12.57 ± 2.97c

13.61 ± 2.10b

  1. Values are mean ± S.E. of three parallel measurements
  2. Different letters indicate significant differences between same concentrations of different extracts and acarbose (p < 0.05, Tukeys HSD test, F-ratio- 63.89 (12.5 μg/mL), 687.88 (25 μg/mL), 3.24E3 (50 μg/mL), 13.29 (100 μg/mL), 212.97 (200 μg/mL), 291.66 (400 μg/mL)
  3. Cornus capitata (4.25% at 1.5 μg/mL; 6% at 3.1 μg/mL and 19% inhibition at 6.25 μg/mL concentration)