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Table 1 α-glucosidase activity of methanolic extracts of different medicinal plants and Acarbose (standard drug)

From: In vitro evaluation of the α-glucosidase inhibitory potential of methanolic extracts of traditionally used antidiabetic plants

Plant Percentage α-glucosidase inhibition (%) IC 50 (μg/mL)
12.5 μg/mL 25 μg/mL 50 μg/mL 100 μg/mL 200 μg/mL 400 μg/mL  
Acarbose (Standard) 18.83 ± 3.87b 30.18 ± 0.06b 42.43 ± 0.05b 56.31 ± 0.02b 80.10 ± 0.15b 89.40 ± 0.09a 66.07
Cornus capitata (Leaves) 63.68 ± 1.98a 97.81 ± 0.03a 98.37 ± 0.12a 97.43 ± 0.18a 97.18 ± 0.18a 94.70 ± 0.41a 12.5
Clematis grata (Whole plant) 0.32 ± 5.79b 4.83 ± 1.46c 5.05 ± 0.74d 5.65 ± 0.75b 8.72 ± 5.09c 13.25 ± 1.10b
Roylea cinerea (Leaves) 8.66 ± 0.20b 9.87 ± 0.16c 10.50 ± 0.66c 14.62 ± 4.20b 15.31 ± 2.60c 20.09 ± 2.21b
Roylea cinerea (Stem) 5.85 ± 1.50b 6.54 ± 3.04c 7.01 ± 1.23d 8.69 ± 1.87b 12.57 ± 2.97c 13.61 ± 2.10b
  1. Values are mean ± S.E. of three parallel measurements
  2. Different letters indicate significant differences between same concentrations of different extracts and acarbose (p < 0.05, Tukeys HSD test, F-ratio- 63.89 (12.5 μg/mL), 687.88 (25 μg/mL), 3.24E3 (50 μg/mL), 13.29 (100 μg/mL), 212.97 (200 μg/mL), 291.66 (400 μg/mL)
  3. Cornus capitata (4.25% at 1.5 μg/mL; 6% at 3.1 μg/mL and 19% inhibition at 6.25 μg/mL concentration)
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