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Table 1 IC50 values (μg/mL) of ferric reducing power, DPPH, PDE-5, arginase, ACE and AChE inhibitory activities in rat penile and testicular tissue by O. gratissimum leaf extracts and standard drugs/inhibitors

From: Ocimum gratissimum Linn. Leaves reduce the key enzymes activities relevant to erectile dysfunction in isolated penile and testicular tissues of rats

Sample PDE-5 (μg/mL) Arginase (μg/mL) ACE (μg/mL) AChE (μg/mL) FRAP (μg/mL) DPPH (μg/mL)
Penis 43.19 ± 0.02c 46.12 ± 0.15c 44.23 ± 0.71a 55.51 ± 0.45a
Testes 44.67 ± 0.01b 49.12 ± 0.12b 53.99 ± 0.85a 60.03 ± 0.34a
Sildenafil (μg/mL) 26.65 ± 0.10a
L-NOHA (μg/mL) 42.48 ± 0.21a
Lisinopril (μg/mL) 38.34 ± 0.01a
Prostigmine (μg/mL) 48.01 ± 1.02a
Vitamin C (μg/mL) 46.16 ± 0.51a 53.81 ± 0.02a
O. gratissimum extract 56.55 ± 0.78a 69.41 ± 0.01a
  1. Values represent mean ± standard deviation (n = 3). Values with the same superscript along the column are not significant (p < 0.05) different. Sildenafil*: standard drug for phosphodiesterase-5 (PDE-5); L-NOHA*: standard inhibitor for arginase; prostigmine*: standard drugs for AChE; Lisinopril*: standard drug for ACE; Vitamin C*: standard drug for ferric reducing power (FRAP) and DPPH