Fig. 4
Effect of treatment with saline or HESc (3, 10 or 30 mg/kg) on the mechanic hypernociception induced by previous intraplantar injection of PGE2 in rats (n = 5 per group). Data are presented as mean ± SEM. #p < 0.05 compared to Saline-Saline group; *p < 0.05 compared to Saline-PGE2 group. Two-way repeated measures ANOVA followed by Bonferroni test