From: Acupuncture in improving endometrial receptivity: a systematic review and meta-analysis
Study | Number of participants (Primary/Secondery) | Finished number | Age (y) | Mean age (y) | experiment | control | Duration | Duration of infertility (y) | BMI | Outcomes (primary/secondary outcome) | Starting time |
---|---|---|---|---|---|---|---|---|---|---|---|
Xiumi You 2018 | E:20 C:20 | E:20 C:20 |  | E:29.4 ± 4.59 C:28.1 ± 3.89 | Warm acupuncture | Medicine | 30 min, qod,3 m |  |  | Pregnancy rate, Endometrial thickness | 7th day of menstruation |
Xuemei Chen 2012 | E:46 C:27 | E:46 C:27 | 20–45 |  | Acupuncture+ medicine | Medicine | 30 min/time,qd |  | 2–12 |  | 7th day of Gn |
Guoqun Luo 2017 | E:25 C:31 | E:25 C:31 | 22–40 | E:33.8 ± 4.6 C:32.5 ± 4.1 | Warm Acupuncture+ Medicine | Medicine | 3 m | E:4.5 ± 2.6 C:4.6 ± 2.3 |  | Pregnancy rate, Endometrial thickness, Endometrial pattern, Embryo transfer rate | After menstruation |
Yanhong Li 2018 | E:46 C:46 | E:46 C:46 | 35–40 | E:37.3 ± 1.2 C:37.5 ± 1.1 | Warm Acupuncture+ Acupoint injection+ Medicine | Medicine | qd |  |  | Endometrial thickness, Endometrial pattern | 5th day of follicular maturation |
Bin Zhou 2012 | E:80 C:70 | E:80 C:70 |  | 29 ± 4 | TEAS+ Medicine | Medicine | 30 min/time,qd | 4 ± 3 |  | Pregnancy rate, Endometrial thickness, Endometrial pattern, RI, PI | After menstruation |
LiqingYu2018 | E:40 C:40 | E:38 C:37 | 21–38 | E:30 ± 4 C:29 ± 5 | Electroacupunctur+Acupuncture+ Medicine | Medicine | 30 min, qod,3 m |  |  | Pregnancy rate, Endometrial thickness, Endometrial pattern, E2, PI | Menstruation |
Qian Chen A 2015 | E:57 C:57 | E:57 C:57 | 24–35 | 31 ± 3 | Acupuncture+ Moxibustion | Medicine | 30 min/time,qd,3 m | E:3.61 ± 1.98 C:3.71 ± 2.21 | E:22.63 ± 3.23 C:22.79 ± 3.73 | Pregnancy rate, Endometrial thickness, Endometrial pattern, RI, PI, High-quality embryo rate |  |
Qian Chen B 2015 | E:20 C:20 | E:20 C:20 | 25–40 | E:35.9 ± 2.9 C:35.9 ± 3.4 | Acupuncture+ Moxibustion | Sham Acupuncture+ Moxibustion | 30 min/time,3 m | E:7 ± 4.4 C:5.3 ± 4 |  | Endometrial thickness, RI, PI | 7th day of menstruation |
Linxin Zhang 2018 | E:14(P:4;S:10) C:12(P:3;S:9) | E:14 C:12 | 20–45 | E:30.3 ± 3.8 C:32.5 ± 4.9 | Acupuncture | Routine treatment | 30 min, qod | E:5.8 ± 3.9 C:4.5 ± 4.1 | E:22.22 ± 3.04 C:20.42 ± 2.11 | Pregnancy rate, Endometrial thickness, E2 | After menstruation |
XiumeiWang2017 | E:30(P:17;S:13) C:30(P:18;S:12) | E:30 C:30 | E:25–40 C:27–42 | E:35.0 ± 3.71 C:34.7 ± 3.18 | Warm acupuncture | Press bean+ Electromagnetic wave lamp | 3 m | E:6.9 ± 3.02 C:6.5 ± 3.09 |  | Pregnancy rate, Endometrial pattern, RI, PI | 10 days before menstruation |
Zhenhong Shuai 2015 | E:34(P:30;S:4) C:34(P:31;S:3) | E:34 C:34 | 25–40 | E:29.4 ± 3.24 C:29.6 ± 2.60 | TEAS | Mock TEAS | 30 min/time, 18 times, 3 m | E:4.56 ± 3.25 C:3.88 ± 2.29 | E:21.99 ± 2.71 C:22.32 ± 1.64 | Pregnancy rate, Endometrial thickness, Embryo transfer rate, Live birth rate | 3th day of menstruation |
Fan Qu 2017 | E:361 C:120 | E:333 C:109 |  |  | TEAS | Routine treatment | 30 min |  |  | Pregnancy rate, High-quality embryo rate, Live birth rate | Before transplant |
Jing Zhong 2017 | E:735(P:305;S:430) C:1026(P:4265;S:600) | E:735 C:1026 | 20–45 | E:31 ± 4 C:32 ± 4 | TEAS | Routine treatment | 30 min/time, 2 times | E:4.8 ± 3.6 C:5 ± 3.6 | E:21.8 ± 3 C:21.8 ± 4.5 | Pregnancy rate | 24 h before transplant |