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Table 1 Characteristics of the included studies

From: Acupuncture in improving endometrial receptivity: a systematic review and meta-analysis

Study

Number of participants (Primary/Secondery)

Finished number

Age (y)

Mean age (y)

experiment

control

Duration

Duration of infertility

(y)

BMI

Outcomes (primary/secondary outcome)

Starting time

Xiumi You

2018

E:20

C:20

E:20

C:20

 

E:29.4 ± 4.59

C:28.1 ± 3.89

Warm acupuncture

Medicine

30 min, qod,3 m

  

Pregnancy rate, Endometrial thickness

7th day of menstruation

Xuemei

Chen

2012

E:46

C:27

E:46

C:27

20–45

 

Acupuncture+ medicine

Medicine

30 min/time,qd

 

2–12

 

7th day of Gn

Guoqun Luo

2017

E:25

C:31

E:25

C:31

22–40

E:33.8 ± 4.6

C:32.5 ± 4.1

Warm Acupuncture+

Medicine

Medicine

3 m

E:4.5 ± 2.6

C:4.6 ± 2.3

 

Pregnancy rate, Endometrial thickness, Endometrial pattern, Embryo transfer rate

After menstruation

Yanhong Li

2018

E:46

C:46

E:46

C:46

35–40

E:37.3 ± 1.2

C:37.5 ± 1.1

Warm Acupuncture+

Acupoint injection+

Medicine

Medicine

qd

  

Endometrial thickness, Endometrial pattern

5th day of follicular maturation

Bin Zhou

2012

E:80

C:70

E:80

C:70

 

29 ± 4

TEAS+

Medicine

Medicine

30 min/time,qd

4 ± 3

 

Pregnancy rate, Endometrial thickness, Endometrial pattern, RI, PI

After menstruation

LiqingYu2018

E:40

C:40

E:38

C:37

21–38

E:30 ± 4

C:29 ± 5

Electroacupunctur+Acupuncture+

Medicine

Medicine

30 min, qod,3 m

  

Pregnancy rate, Endometrial thickness, Endometrial pattern, E2, PI

Menstruation

Qian Chen A

2015

E:57

C:57

E:57

C:57

24–35

31 ± 3

Acupuncture+

Moxibustion

Medicine

30 min/time,qd,3 m

E:3.61 ± 1.98

C:3.71 ± 2.21

E:22.63 ± 3.23

C:22.79 ± 3.73

Pregnancy rate, Endometrial thickness, Endometrial pattern, RI, PI, High-quality embryo rate

 

Qian Chen B

2015

E:20

C:20

E:20

C:20

25–40

E:35.9 ± 2.9

C:35.9 ± 3.4

Acupuncture+

Moxibustion

Sham Acupuncture+

Moxibustion

30 min/time,3 m

E:7 ± 4.4

C:5.3 ± 4

 

Endometrial thickness, RI, PI

7th day of menstruation

Linxin

Zhang

2018

E:14(P:4;S:10)

C:12(P:3;S:9)

E:14

C:12

20–45

E:30.3 ± 3.8

C:32.5 ± 4.9

Acupuncture

Routine treatment

30 min, qod

E:5.8 ± 3.9

C:4.5 ± 4.1

E:22.22 ± 3.04

C:20.42 ± 2.11

Pregnancy rate, Endometrial thickness, E2

After menstruation

XiumeiWang2017

E:30(P:17;S:13)

C:30(P:18;S:12)

E:30

C:30

E:25–40

C:27–42

E:35.0 ± 3.71

C:34.7 ± 3.18

Warm acupuncture

Press bean+

Electromagnetic wave lamp

3 m

E:6.9 ± 3.02

C:6.5 ± 3.09

 

Pregnancy rate, Endometrial pattern, RI, PI

10 days before menstruation

Zhenhong Shuai

2015

E:34(P:30;S:4)

C:34(P:31;S:3)

E:34

C:34

25–40

E:29.4 ± 3.24

C:29.6 ± 2.60

TEAS

Mock TEAS

30 min/time, 18 times, 3 m

E:4.56 ± 3.25

C:3.88 ± 2.29

E:21.99 ± 2.71

C:22.32 ± 1.64

Pregnancy rate, Endometrial thickness, Embryo transfer rate, Live birth rate

3th day of menstruation

Fan Qu 2017

E:361

C:120

E:333

C:109

  

TEAS

Routine treatment

30 min

  

Pregnancy rate, High-quality embryo rate, Live birth rate

Before transplant

Jing Zhong

2017

E:735(P:305;S:430)

C:1026(P:4265;S:600)

E:735

C:1026

20–45

E:31 ± 4

C:32 ± 4

TEAS

Routine treatment

30 min/time, 2 times

E:4.8 ± 3.6

C:5 ± 3.6

E:21.8 ± 3

C:21.8 ± 4.5

Pregnancy rate

24 h before transplant