Fig. 6From: Effects of resveratrol on Th17 cell-related immune responses under tacrolimus-based immunosuppressionSkin allograft survival in mice treated with Resv and Tac. (a) Kaplan-Meier Survival curve of skin allografts in each group with six animals per group. (b, c) The proportion (%) of IFN-γ+/CD4+ T cells, and IL-17+/CD4+ T cells in isolated spleen cells from each group was measured via flow cytometry in six animals per group. (d) Histological changes in skin allografts at day 6. The inflammatory cell infiltration of the skin allograft was significantly reduced in the Tac alone group compared to the control group. Combined use of Tac and Resv further decreased inflammatory cell infiltration in skin graft tissue (Magnification × 400). *P < 0.05 vs Control †P < 0.05 vs. Tac 2 mg/kg group. Resv, Resveratrol; Tac, tacrolimusBack to article page