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Table 3 Histomorphometrical analysis on the fundus, taken from intact or IND-treated rats

From: Protective effects of triple fermented barley extract (FBe) on indomethacin-induced gastric mucosal damage in rats

Items (Unit) groups

Histomorphometry (at sacrifice)

Invasive percentages of lesions* (%)

Mean peri-ulcerative mucosa thickness (μm)

Semiquantitative scores (Max = 3)

Control

 Intact

4.27 ± 2.87

902.66 ± 131.22

0.38 ± 0.52

 IND

68.53 ± 12.68e

281.50 ± 87.64a

2.75 ± 0.46a

Reference

 OM 10 mg kg− 1

26.65 ± 15.66e,f

538.88 ± 87.26a,b

1.38 ± 0.52a,b

FBe treated as

 100 mg kg− 1

32.59 ± 14.44e,f

410.09 ± 58.15a,c

2.00 ± 0.53a,b

 200 mg kg− 1

25.63 ± 10.67e,f

521.04 ± 90.25a,b

1.50 ± 0.53a,b

 300 mg kg− 1

13.00 ± 5.46e,f

635.59 ± 129.75a,b

1.13 ± 0.64a,b

  1. Values are expressed as mean ± S.D. of eight rat samples
  2. FBe triple fermented barley extract as test material, IND indomethacin, OM omeprazole
  3. *\( \mathrm{Invasive}\ \mathrm{percentage}\ \mathrm{of}\ \mathrm{lesions}\ \left(\%\right)=\left(\frac{\mathrm{Length}\ \mathrm{of}\ \mathrm{lesions}\ \mathrm{on}\ \mathrm{the}\ \mathrm{crossly}\ \mathrm{trimmed}\ \mathrm{fundic}\ \mathrm{walls}}{\mathrm{Total}\ \mathrm{thickness}\ \mathrm{of}\ \mathrm{crossly}\ \mathrm{trimmed}\ \mathrm{fundic}\ \mathrm{walls}}\right)\ \mathrm{x}\ 100 \)
  4. Semiquantitative scoring was divided into four groups; 0: normal intact mucosa, 1: slight surface erosive damages, 2: moderate mucosa damages, and 3: severe total mucosa damages
  5. ap < 0.01 as compared with intact control by LSD test
  6. bp < 0.01 and cp < 0.05 as compared with IND control by LSD test
  7. dp < 0.01 as compared with intact control by MW test
  8. ep < 0.01 as compared with IND control by MW test