Fig. 6

HO-1 expression by STL and STB is through Nrf2 activation dependent on ROS-mediated p38 activation. a SW480 cells were treated with STL and STB for 24 h. b SW480 cells were pretreated with SB203580 (20 μM) or NAC (20 mM) for 2 h, and then co-treated with STL and STB for the additional 24 h. c SW480 cells were treated with STL and STB for the indicated times. d SW480 cells were treated with NAC (20 mM) for 2 h, and then co-treated with STL and STB for the additional 24 h. Actin, TBP or total-p38 was used as loading control. ^*P < 0.05 compared to the cells without STL and STB