Fig. 4

Cyclin D1 degradation by STL and STB is dependent on GSK3β. a SW480 cells were treated with LiCl (20 mM) for 2 h, and then co-treated with STL and STB for the additional 6 h. b SW480 cells were treated with LiCl (20 mM) for 2 h, and then co-treated with STL and STB for the additional 1 h. c SW480 cells were treated with STL and STB for the indicated times. d SW480 cells were treated with LMB (50 ng/ml) for 2 h, and then co-treated with STL and STB for the additional 6 h. Actin was used as loading control. ^*P < 0.05 compared to the cells without STL and STB