Skip to main content

Table 3 Bacteriostatic and bactericidal efficacy of selected lipids and its active components against logarithmic and stationary phases of Borrelia burgdorferii s.s. and Borrelia garinii

From: Anti-borreliae efficacy of selected organic oils and fatty acids

Tested agents

Borrelia burgdorferi s.s.

Borrelia garinii

Logarithmic phase

Stationary phase

Logarithmic phase

Stationary phase

MIC

MBC90

MBC90

MIC

MBC90

MBC90

Bay leaf oil

0.0005%

0.15%

0.15%

0.0005%

0.15%

0.15%

Eugenol

0.0003%

0.125%

0.125%

0.0003%

0.125%

0.125%

Birch oil

0.00075%

0.25%

0.25%

0.00075%

0.25%

0.25%

Methyl Salicylate

0.00075%

0.25%

0.25%

0.00075%

0.25%

0.25%

Cassia oil

0.0005%

0.15%

0.15%

0.0005%

0.15%

0.15%

Cinnamaldehyde

0.0003%

0.125%

0.125%

0.0003%

0.125%

0.125%

Chamomile oil

0.0075%

0.25%

0.25%

0.0075%

0.25%

0.25%

Chamazulene

0.01 mg/ml

0.10 mg/ml

0.10 mg/ml

0.01 mg/ml

0.10 mg/ml

0.10 mg/ml

α-bisabalol

NSa

NSa

NSa

NSa

NSa

NSa

Thyme oil

0.0005%

0.20%

0.20%

0.0005%

0.20%

0.20%

Thymol

0.02 mg/ml

0.20 mg/ml

0.20 mg/ml

0.025 mg/ml

0.20 mg/ml

0.20 mg/ml

γ-terpinene

NSa

NSa

NSa

NSa

NSa

NSa

13Z,16Z Docosadienoic acid

0.025 mg/ml

0.50 mg/ml

0.50 mg/ml

0.025 mg/ml

0. 05 mg/ml

0.50 mg/ml

  1. Abbreviations: MIC–minimal bacteriostatic concentration causing at least 90% of growth inhibition assessed by direct courting using dark field microscopy after 72 h of treatment MBC90–minimal bactericidal concentration causing at least 90% of killing assessed using by direct courting using fluorescence microscopy after 72 h of treatment, a–maximal tested concentration (i.e., 1%), NS–not susceptible/not satisfying MIC/MBC90 requirement at the maximal tested concentration