Sample | %Inhibition at various concentration (μg/mL) (%Viability) | IC50(μg/mL) | ||||
---|---|---|---|---|---|---|
0.01 | 0.1 | 1 | 10 | 50 | ||
Crude extract | – | 16.65 ± 6.18 (92.51 ± 2.14) | 32.42 ± 5.42 (89.44 ± 3.74) | 54.64 ± 2.23 (83.49 ± 2.66) | 68.38 ± 1.04 (78.82 ± 2.83) | 6.06 ± 0.43* |
Compound 1 | – | 2.66 ± 0.23 (84.66 ± 7.91) | 3.91 ± 3.03 (89.71 ± 12.08) | 14.41 ± 1.71 (84.71 ± 9.65) | 69.15 ± 2.49 (80.46 ± 3.10) | 40.40 ± 1.32* |
Compound 2 | – | 7.09 ± 6.86 (94.52 ± 10.55) | 11.12 ± 9.89 (88.81 ± 8.07) | 8.69 ± 6.93 (80.85 ± 7.39) | 58.83 ± 3.59 (90.39 ± 9.92) | 33.61 ± 5.25* |
Compound 3 | – | −0.82 ± 3.26 (102.40 ± 2.17) | 2.64 ± 0.31 (96.95 ± 0.98) | 14.59 ± 3.43 (97.27 ± 4.43) | 34.44 ± 3.07 (91.62 ± 3.87) | > 50* |
Prednisolone (Positive control) | 19.82 ± 3.43 (100.40 ± 12.94) | 47.72 ± 6.24 (84.28 ± 4.56) | 69.94 ± 3.76 (89.46 ± 2.28) | 77.94 ± 8.12 (80.78 ± 2.71) | – | 0.11 ± 0.02 |