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Table 2 Effect of oral administration of OE on urinalysis parameters in male and female rats

From: An oral toxicity test in rats and a genotoxicity study of extracts from the stems of Opuntia ficus-indica var. saboten

Tests Result Grade Male Female
G1 G2 G3 G4 G1 G2 G3 G4
GLU 0 3 3 3 3 3 3 3 3
BIL 0 3 3 3 3 3 3 3 3
KET 0 2 2 2 0 3 3 3 2
+/− 1 1 1 1 3 0 0 0 1
SG ≤1.005 0 0 0 0 0 1 0 0 0
1.010 1 0 0 1 0 2 1 1 0
1.015 2 0 0 0 1 0 1 2 1
1.020 3 0 2 1 0 0 1 0 1
1.025 4 3 1 1 1 0 0 0 1
≥1.030 5 0 0 0 1 0 0 0 0
pH 6.5 0 1 0 0 1 0 0 0 0
7.0 1 0 2 0 1 0 0 0 0
7.5 2 1 0 1 0 3 3 3 2
8.0 3 1 0 2 1 0 0 0 1
8.5 4 0 1 0 0 3 3 3 1
PRO 0 0 0 1 0 0 0 0 2
+/− 1 0 0 1 1 3 3 3 3
1+ 2 3 3 1 2 3 3 3 3
URO 0.2 0 3 3 3 3 3 2 2 3
NIT 0 3 3 3 3 0 0 1 0
BLO 0 3 3 3 3 0 1 0 0
LEU 0 2 1 1 0 3 3 3 3
+/− 1 0 2 1 1 3 3 3 3
1+ 2 1 0 1 2 3 3 3 3
Clarity 0 3 3 3 3 3 3 3 3
Color-Yellow 3 3 3 3 3 3 3 3
  1. G1: negative control; G2: 500 mg/kg OE treated group; G3: 1000 mg/kg OE treated group; G4: 2000 mg/kg OE treated group. GLU: glucose (mg/dL); BIL: bilirubin (mg/dL); KET: ketone bodies (mg/dL); SG: specific gravity; PRO: protein (mg/dL); URO: urobilinogen (mg/dL); NIT: nitrites (mg/dL); BLO: Occult blood: LEU: leukocytes (Leu/dL). Results were analyzed using the non-parametric Kruskal-Wallis test but there were no significance differences among the groups