Fig. 4From: 2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells2-Ethoxystypandrone (1) inhibited self-renewal, cell growth and the tumorsphere formation of HCC CSCs in dose-dependent manner. a. HCC CSCs were treated with 2-ethoxystypandrone (1) at the indicated concentration for 72 h. b. Number of tumorspheres after being treated with 2-ethoxystypandrone (1) at the indicated concentration for 72 h. Values are means + SEM, *p < 0.05 and ***p < 0.001, compared to control group. One-way ANOVA was used for statistical analysis by SPSS 19.0 software. c. The growth curve of the tumorspheres after being treated 2-ethoxystypandrone (1) at the indicated concentration for 72 hBack to article page