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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro

Fig. 1

Concentration-dependent inhibition of MCF-7 cell proliferation by treatment for 7 days with (a) VAEM, (b) endoxifen, both in the presence or absence of 0.5 μM β-estradiol, (c) VAEM and endoxifen in the presence of 0.5 μM β-estradiol (E2) and (d) VAEM and endoxifen in the absence of β-estradiol. Cell growth kinetics was assessed with the WST-1 assay. Results are presented as % relative to untreated control (mean ± SE from three independent experiments). Significances are given relative to the VAEM untreated values (*p < 0.05, **p < 0.01, ***p < 0.001)

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