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Table 2 Cytokines and receptors showing significant differential gene expression level in the liver of infected AG129 mice treated with FCPLJa compared to infected AG129 mice without treatment

From: Effect of freeze-dried Carica papaya leaf juice on inflammatory cytokines production during dengue virus infection in AG129 mice

Gene target Description Fold regulationb P valuec
CCL12 Chemokine (c-c motif) ligand 12 −2.31 0.000161
CCL17 Chemokine (c-c motif) ligand 17 −2.76 0.013469
CCL6 Chemokine (c-c motif) ligand 6 −2.23 0.000039
CCL8 Chemokine (c-c motif) ligand 8 −5.05 0.045934
IL1R1 Interleukin-1 receptor, type 1 −2.95 0.037396
IL1RN Interleukin-1 receptor antagonist −4.99 0.011812
NAMPT Nicotinamide phosphoribosyltransferase −1.92 0.016427
PF4 Platelet factor 4 −2.21 0.035662
  1. aFreeze-dried Carica papaya leaf juice; dengue virus infected AG129 mice were given 1000 mg/kg BW
  2. bThe fold regulation cut off is 1.5
  3. cGene expression are considered to show significant differential expression at a P value of < 0.05