Group Treatment | Blood glucose (mmol/L) | Insulin concentration (pg/mL) | Body weight (g) | Food intake (g) | Water consumption (mL) | |||||
---|---|---|---|---|---|---|---|---|---|---|
Day 7 | Day 14 | Day 7 | Day 14 | Day 7 | Day 14 | Day 7 | Day 14 | Day 7 | Day 14 | |
Normal | 5.2 ± 0.7 | 4.9 ± 0.1 | 40.5 ± 4.4 | 46.7 ± 7.1 | 280.3 ± 18.8 | 312.7 ± 17 | 130.5 ± 14.4 | 193.9 ± 4.0 | 246.6 ± 5.8 | 393.0 ± 3.7 |
Diabetic | 22.2 ± 1.2 | 20.7 ± 2.4 | 5.1 ± 0.1 | 7.1 ± 0.8 | 235.0 ± 22.5 | 208.7 ± 3.3 | 152.6 ± 2.3 | 260.6 ± 10.0 | 617.9 ± 14.4 | 967.9 ± 9.5 |
VCN-2 film | ||||||||||
 12.5 μM | 17.1 ± 0.2 | 14.4 ± 2.7 | 12.8 ± 3.1 | 27.4 ± 0.6 | 253.4 ± 9.7 | 268.7 ± 3.4 | 144.8 ± 11.5 | 247.0 ± 9.6 | 598.6 ± 17.3 | 927.2 ± 17.3 |
 25 μM | 16.0 ± 0.3 | 14.4 ± 1.0 | 21.5 ± 0.3 | 27.7 ± 0.9 | 251.0 ± 25.5 | 277.7 ± 2.6 | 140.0 ± 5.8 | 243.6 ± 11.5 | 589.3 ± 13.2 | 867.9 ± 13.2 |
 50 μM | 21.1 ± 1.7 | 15.3 ± 3.3 | 23.2 ± 3.0 | 31.3 ± 4.3 | 260.2 ± 31.5 | 280.2 ± 3.5 | 133.3 ± 12.6 | 235.4 ± 14.5 | 574.3 ± 14.4 | 845.7 ± 28.8 |
ALN film | ||||||||||
 316 μM | 20.7 ± 1.6 | 14.0 ± 1.3 | 29.2 ± 3.8 | 30.7 ± 4.0 | 236.0 ± 30.7 | 248.8 ± 5.8 | 139.4 ± 8.7 | 245.1 ± 14.4 | 584.3 ± 28.8 | 862.8 ± 25.1 |