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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: The ethanolic extract of Aralia continentalis ameliorates cognitive deficits via modifications of BDNF expression and anti-inflammatory effects in a rat model of post-traumatic stress disorder

Fig. 5

Effects of AC on brain-derived neurotrophic factor (BDNF) and cAMP-response element-binding protein (CREB) protein levels (a and b) and mRNA expression in the hippocampus of rats with SPS-induced memory impairment. Polymerase chain reaction (PCR) bands on agarose gels and relative intensities are shown in (c). The mRNA expression levels of BDNF and CREB were normalized to that of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) mRNA as an internal control (n = 4/group). *p < 0.05, **p < 0.01 vs. the CON group, #p < 0.05, ##p < 0.01 vs. the SPS group

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