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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Danggui Buxue Tang, an ancient Chinese herbal decoction, protects β-amyloid-induced cell death in cultured cortical neurons

Fig. 4

DBT regulates expressions of Bcl2 and Bax. Cultured cortical neurons were co-treated with various concentration of DBT (DBT-L: 12.5 μg/mL; DBT-H: 100 μg/mL) and Aβ (20 μM) for 48 h. The protein expression levels of Bcl2 (~ 27 kDa) and Bax (~ 21 kDa) were detected by immunoblot analysis using specific antibodies, and β-actin (~ 42 kDa) served as an internal control. Quantification of target protein expression was calculated by a densitometer. Values were expressed as the percentage of change as compared to control reading, in Mean ± SEM, where n = 3. Statistically significant changes were classified as more significant (**) where p < 0.01 and highly significant (***) where p < 0.001 as compared with control group. More significant (^^) where p < 0.01 and highly significant (^^^) where p < 0.001 are compared with Aβ group

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