Settings: Outpatients
|
Intervention: Enteric-coated Peppermint Oil Capsules vs. Placebo
|
Outcomes
|
Illustrative Comparative Risk*
| | | | |
Assumed risk
|
Corresponding risk
| | | | |
Control (per 1000)
|
Peppermint Oil vs. Placebo (per 1000)
|
Relative Risk (95% CI)
|
No. Participants (Studies)
|
Quality of Evidence (GRADE)
|
NNT (95% CI)
|
Global improvement in IBS symptoms
|
250†
|
598 (483 to 743)
|
2.39 (1.93–2.97)
|
507 (7)
| ⨁⨁⨁⨁‡ High |
3 (2–4)
|
Improvement in abdominal pain
|
303†
|
539 (433 to 666)
|
1.78 (1.43–2.20)
|
556 (6)
| ⨁⨁⨁◯§ Moderate |
4 (3–6)
|
Adverse events
|
21†
|
29 (18 to 47)
|
1.40 (0.87–2.26)
|
671 (8)
| ⨁⨁◯◯ǁ Low |
125 (29-∞)
|