Probiotics and yogurt modulate oxidative stress and fibrosis in livers of Schistosoma mansoni -infected mice

Table 3 Effects of probiotics or yogurt administration on worm burden, liver tissue eggs load, granuloma size and count of S. mansoni infected mice

Groups	Mean number of worms ± SEM	Reduction on worm burden (%)	Ova count in liver (ova/mg tissue) ± SEM	Reduction on ova count (%)	Granuloma size (μm²)	Granuloma number per area (mm)
Vehicle control	17.4 ± 2.47	–	11.4 ± 1.08	–	1,103,658 ± 2106	11.6 ± 2.3
PZQ	3.8 ± 1.12^a	78.2	2.3 ± 0.71^a	79.8	864,627 ± 1137^a	6.2 ± 1.7^a
Pre-Probiotics+infection	5.6 ± 1.41^a	67.8	3.1 ± 0.21^a	72.8	984,273 ± 1637^a	8.1 ± 1.2^a
Probiotics+infection	7.0 ± 0.89^a	59.8	5.2 ± 0.39^a	54.4	1,067,435 ± 2318	9.4 ± 2.3^a
Pre-Yogurt+infection	4.8 ± 1.28^a	72.4	2.7 ± 0.34^a	76.3	361,474 ± 864^a	5.8 ± 2.1^a
Yogurt+infection	6.2 ± 1.06^a	64.4	4.3 ± 0.28^a	62.3	635,417 ± 1268^a	6.9 ± 1.8^a

Values are means ± SEM (n = 7). ^ap < 0.05, significant change with respect to Vehicle control