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Table 3 Effects of probiotics or yogurt administration on worm burden, liver tissue eggs load, granuloma size and count of S. mansoni infected mice

From: Probiotics and yogurt modulate oxidative stress and fibrosis in livers of Schistosoma mansoni-infected mice

Groups

Mean number of worms ± SEM

Reduction on worm burden (%)

Ova count in liver (ova/mg tissue) ± SEM

Reduction on ova count (%)

Granuloma size (μm2)

Granuloma number per area (mm)

Vehicle control

17.4 ± 2.47

–

11.4 ± 1.08

–

1,103,658 ± 2106

11.6 ± 2.3

PZQ

3.8 ± 1.12a

78.2

2.3 ± 0.71a

79.8

864,627 ± 1137a

6.2 ± 1.7a

Pre-Probiotics+infection

5.6 ± 1.41a

67.8

3.1 ± 0.21a

72.8

984,273 ± 1637a

8.1 ± 1.2a

Probiotics+infection

7.0 ± 0.89a

59.8

5.2 ± 0.39a

54.4

1,067,435 ± 2318

9.4 ± 2.3a

Pre-Yogurt+infection

4.8 ± 1.28a

72.4

2.7 ± 0.34a

76.3

361,474 ± 864a

5.8 ± 2.1a

Yogurt+infection

6.2 ± 1.06a

64.4

4.3 ± 0.28a

62.3

635,417 ± 1268a

6.9 ± 1.8a

  1. Values are means ± SEM (n = 7). ap < 0.05, significant change with respect to Vehicle control