Fig. 3From: Jian-Pi-Yi-Shen Formula ameliorates chronic kidney disease: involvement of mitochondrial quality control networkJPYSF ameliorates renal pathological injury in 5/6 Nx rats. a PAS staining shows significant improvement of glomerular hypertrophy and tubular atrophy in the 5/6 Nx + JPYSF group. All images are shown at identical magnification, the upper panel × 200, scale bar = 100 μm; the lower panel × 400, scale bar = 50 μm. Quantitative analyses of (b) glomerular tuft area and (c) proximal tubular lumen cross-sectional area in each group. d Masson staining indicates reduced fibrosis after JPYSF treatment. All images are shown at identical magnification, × 200, scale bar = 100 μm. For (b) and (c), 40–50 glomerular tuft area and 40–50 proximal tubular lumen cross-sectional area in each rat and five rats in each group were measured. Data are presented as the means ± SEM, n = 5 rats per group. (**P < 0.01 compared with the sham group; ##P < 0.01 compared with the 5/6 Nx group; δδP < 0.01 compared with the 5/6 Nx + Perindopril group)Back to article page