TY - JOUR AU - Lenzi, Monia AU - Cocchi, Veronica AU - Novaković, Aleksandra AU - Karaman, Maja AU - Sakač, Marijana AU - Mandić, Anamarija AU - Pojić, Milica AU - Barbalace, Maria Cristina AU - Angeloni, Cristina AU - Hrelia, Patrizia AU - Malaguti, Marco AU - Hrelia, Silvana PY - 2018 DA - 2018/11/12 TI - Meripilus giganteus ethanolic extract exhibits pro-apoptotic and anti-proliferative effects in leukemic cell lines JO - BMC Complementary and Alternative Medicine SP - 300 VL - 18 IS - 1 AB - The interest towards botanicals and plant extracts has strongly risen due to their numerous biological effects and ability to counteract chronic diseases development. Among these effects, chemoprevention which represents the possibility to counteract the cancerogenetic process is one of the most studied. The extracts of mushroom Meripilus giganteus (MG) (Phylum of Basidiomycota) showed to exert antimicrobic, antioxidant and antiproliferative effects. Therefore, since its effect in leukemic cell lines has not been previously evaluated, we studied its potential chemopreventive effect in Jurkat and HL-60 cell lines. SN - 1472-6882 UR - https://doi.org/10.1186/s12906-018-2366-7 DO - 10.1186/s12906-018-2366-7 ID - Lenzi2018 ER -