The composition of a bioprocessed shiitake (Lentinus edodes) mushroom mycelia and rice bran formulation and its antimicrobial effects against Salmonella enterica subsp. enterica serovar Typhimurium strain SL1344 in macrophage cells and in mice

Table 3 Effect of NPRBE and BPRBE on bacterial load in feces and organs from Salmonella-infected mice

	Treatment
	Salmonella infection only	NPRBE (10 mg/kg)	BPRBE (10 mg/kg)
Salmonella in feces (× 10⁵ CFU/g)
1 day	338 ± 18^b	347 ± 21^b	662 ± 48^a
2 day	420 ± 31^b	448 ± 35^b	729 ± 53^a
Salmonella in organs
Cecum (× 10⁵ CFU/g)	35.3 ± 2.7^a	30.6 ± 1.5^a	15.4 ± 1.3^b
Mesenteric lymph node (× 10³ CFU/organ)	34.7 ± 1.9^a	31.4 ± 2.7^a	8.8 ± 0.6^b
Spleen (× 10² CFU/organ)	172.1 ± 8.8^a	165.3 ± 11.2^a	10.5 ± 0.9^b
Liver (× 10² CFU/organ)	80.6 ± 7.6^a	75.4 ± 2.9^a	9.6 ± 0.7^b

Data are expressed as the mean ± SD (n = 3). Values in each row with the same letter are not significantly different between groups at p < 0.05. BPRBE, bioprocessed rice bran extract; NPRBE, non-processed rice bran extract

ISSN: 2662-7671