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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Baicalin promotes apoptosis and inhibits proliferation and migration of hypoxia-induced pulmonary artery smooth muscle cells by up-regulating A2a receptor via the SDF-1/CXCR4 signaling pathway

Fig. 4

Baicalin intervention enhanced A2aR expression. a: Images and quantitave analysis of A2aR expression in PASMCs by western blot assay. Tubulin served as an internal control. b: Rt-qPCR indicated that baicalin upregulated A2aR mRNA in hypoxic PASMCs. c: SDF-1 expression increased in KD/H + Bai group compared with H + Bai group. d: CXCR4 expression increased in KD/H + Bai group compared with H + Bai group. # P < 0.05, ##p < 0.01 vs normoxia group, * P < 0.05 **P < 0.01 vs hypoxia group; + p < 0.05, ++ p < 0.01 Comparison between groups. n = 3

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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