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Table 1 Body weight gain in sham-operated and OVX mice

From: Anti-osteoporotic effects of mixed compositions of extracellular polymers isolated from Aureobasidium pullulans and Textoria morbifera in ovariectomized mice

Periods
Groups
Body weights (g) Body weight gains (g)
At OVX
[A]*
At 34 days after OVX [B] At initial treatment [C]* At sacrifice
[D]*
OVX recovery
[B-A]
Treatment
[D-C]
Controls
 Sham 25.55 ± 1.62 33.86 ± 2.53 29.90 ± 2.56 31.45 ± 2.74 8.31 ± 1.88 1.46 ± 0.92
 OVX 25.51 ± 1.20 37.40 ± 3.22b 33.96 ± 2.84a 37.59 ± 2.75a 11.89 ± 2.90a 3.63 ± 0.73a
Reference (2.5 mg/kg)
 RES 26.29 ± 0.80 36.68 ± 1.71b 33.40 ± 1.68b 35.75 ± 2.80a 10.39 ± 1.53b 2.35 ± 2.11
Single formula (200 mg/kg)
 EAP 26.61 ± 1.59 37.70 ± 3.22a 34.00 ± 2.62a 35.08 ± 1.90a 11.09 ± 3.11b 1.08 ± 1.76c
 TM 25.99 ± 1.35 37.31 ± 3.20b 34.10 ± 2.99a 35.06 ± 2.57a 11.33 ± 2.55 a 0.96 ± 0.78c
Mixed formula - EAP:TM (200 mg/kg)
 1:1 25.60 ± 1.82 36.59 ± 1.87 33.18 ± 1.83b 34.53 ± 2.11bd 10.99 ± 2.10a 1.35 ± 1.47c
 1:3 26.80 ± 2.21 37.63 ± 3.03a 34.26 ± 2.74a 35.24 ± 3.58a 10.83 ± 2.29b 0.98 ± 1.41c
 1:5 25.60 ± 1.01 37.58 ± 2.92b 33.80 ± 2.63a 34.69 ± 3.91bd 11.98 ± 3.34a 0.89 ± 2.03c
 1:7 26.73 ± 1.88 37.49 ± 2.95b 33.84 ± 2.53a 34.91 ± 2.49b 10.79 ± 2.27b 1.08 ± 2.23c
 1:9 26.39 ± 1.14 37.55 ± 2.98b 34.08 ± 2.67a 35.23 ± 1.75a 11.16 ± 2.53a 1.15 ± 1.73c
 3:1 25.93 ± 1.27 37.51 ± 2.99b 33.79 ± 2.76a 32.76 ± 2.66c 11.59 ± 2.83a - 1.03 ± 1.43acef
 5:1 26.13 ± 1.24 37.54 ± 2.87b 34.00 ± 2.75a 34.99 ± 2.52b 11.41 ± 3.27a 0.99 ± 1.92c
 7:1 26.11 ± 0.96 37.48 ± 2.89b 33.96 ± 2.69a 34.91 ± 3.10b 11.36 ± 2.62a 0.95 ± 1.25c
 9:1 26.44 ± 1.66 37.50 ± 2.80b 34.05 ± 2.79a 35.05 ± 2.15a 11.06 ± 2.50a 1.00 ± 1.71c
  1. OVX Bilateral ovariectomy, RES Risedronate sodium, EAP Exopolymers purified from A. pullulans SM2001, TM T. morbifera leaf extracts, (EAP:TM) Mixed formula consisted of EAP and TM (g/g)
  2. Values are expressed mean ± S.D. of eight mice
  3. *All animals were overnight fasted
  4. ap < 0.01 and bp < 0.05 as compared with sham control by LSD test
  5. cp < 0.01 and dp < 0.05 as compared with OVX control by LSD test
  6. ep < 0.05 as compared with EAP single formula treated mice by LSD test
  7. fp < 0.05 as compared with TM single formula treated mice by LSD test