Fig. 4

Neuroprotective effect of SGT and SGT166 against toxicant-induced SH-SY5Y cell loss. Cells were pretreated with SGT or SGT166 for 6 h, and then separately exposed to 50 μM H₂O₂ (a) and 50 μM etoposide (b) for 24 h. Cell viability was determined by CCK analysis and the results are expressed as the percentages of viable cells compared to the cells untreated with any toxicant. The values shown are means ± SE (n = 5). ^**P < 0.01 and ^***P < 0.001 versus the cells treated with toxicant only