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Table 1 Information of active compound by ADME filtering

From: Investigate the mechanisms of Chinese medicine Fuzhengkangai towards EGFR mutation-positive lung adenocarcinomas by network pharmacology

ID compounds Structure OB Caco.2 DL Herbs
MOL000049 3β-acetoxyatractylone 54.07 1.13 0.22 Atractylodes Macrocephala Koidz.
MOL000296 hederagenin 36.91 1.32 0.75 Curcumae Rhizoma
MOL000358 beta-sitosterol 36.91 1.32 0.75 Hedyotis Diffusae Herba
MOL000371 3,9-di-O-methylnissolin 53.74 1.18 0.48 Hedysarum multijugum Maxim.
MOL000378 7-O-methylisomucronulatol 74.69 1.08 0.3 Hedysarum Multijugum Maxim.
MOL000380 (6aR,11aR)-9,10-dimethoxy-6a,11a-dihydro-6H-benzofurano[3,2-c]chromen-3-ol 64.26 0.93 0.42 Hedysarum Multijugum Maxim.
MOL000392 Formononetin 69.67 0.78 0.21 licorice
MOL000417 Calycosin 47.75 0.52 0.24 licorice
MOL000449 Stigmasterol 43.83 1.44 0.76 Hedyotis Diffusae Herba
MOL000497 licochalcone a 40.79 0.82 0.29 licorice
MOL000500 Vestitol 74.66 0.86 0.21 licorice
MOL000546 Diosgenin 80.88 0.82 0.81 Solanum nigrum Linn
MOL001484 Inermine 75.18 0.89 0.54 licorice
MOL001670 2-methoxy-3-methyl-9,10-anthraquinone 37.83 0.73 0.21 Hedyotis Diffusae Herba
MOL002565 Medicarpin 49.22 1 0.34 licorice
MOL002773 beta-carotene 37.18 2.25 0.58 Solanum Nigrum Linn
MOL003896 7-Methoxy-2-methyl isoflavone 42.56 1.16 0.2 licorice
MOL004835 Glypallichalcone 61.6 0.76 0.19 licorice
MOL004841 Licochalcone B 76.76 0.47 0.19 licorice
MOL004857 Gancaonin B 48.79 0.58 0.45 licorice
MOL004866 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-
(3-methylbut-2-enyl)chromone
44.15 0.48 0.41 licorice
MOL004891 shinpterocarpin 80.3 1.1 0.73 licorice
MOL004908 Glabridin 53.25 0.97 0.47 licorice
MOL004911 Glabrene 46.27 0.99 0.44 licorice
MOL004945 (2S)-7-hydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl) chroman-4-one 36.57 0.72 0.32 licorice
MOL004957 HMO 38.37 0.79 0.21 licorice
MOL004959 1-Methoxyphaseollidin 69.98 1.01 0.64 licorice
MOL004966 3’-Hydroxy-4’-O-Methylglabridin 43.71 1 0.57 licorice
MOL004974 3′-Methoxyglabridin 46.16 0.94 0.57 licorice
MOL004978 2-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[6,5-f]chromen-3-yl]-5-methoxyphenol 36.21 1.12 0.52 licorice
MOL004980 Inflacoumarin A 39.71 0.73 0.33 licorice
MOL004991 7-Acetoxy-2-methylisoflavone 38.92 0.74 0.26 licorice
MOL005003 Licoagrocarpin 58.81 1.23 0.58 licorice
MOL005007 Glyasperins M 72.67 0.49 0.59 licorice
MOL005020 dehydroglyasperins C 53.82 0.68 0.37 licorice