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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Free radical scavenging, α-glucosidase inhibitory and lipase inhibitory activities of eighteen Sudanese medicinal plants

Fig. 1

Imaging of genotoxicity of Sudanese medicinal plants in HeLa cells using the HCS DNA Damage Kit, (a) Chart showing the relative genotoxicity level of the 70% ethanol and water extracts of five Sudanese medicinal plants (AN: Acacia nilotica, ZS: Ziziphus spina-christi, GA: Geigeria alata. MA: Martynia annua AP: Abrus precatorius; For each extract, 70 represents 70% EtOH extract and W represents water extract), (b) Cells treated with 70% ethanolic extracts; (c) Cells treated with water extracts; (d) Positive control experiment, HeLa cells were treated with 120 μM valinomycin for 24 h at 37 °C/5% CO2. Imaging and analysis were performed using a BZ-X700. At 120 μM valinomycin, cells showed genotoxic effects as demonstrated by the positive pH2AX. The level of genotoxicity in the control experiment was set as 1.0. The fold change in signal between treated samples and control was > 3-fold for a parameter indicating genotoxicity

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