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Table 4 Effect of MECN on thiopental sodium induced hypnosis

From: The leaves of Crataeva nurvala Buch-Ham. modulate locomotor and anxiety behaviors possibly through GABAergic system

Treatment

Dose (mg/kg)

Responses

Onset of sleeping

Sleeping duration

Control

0.1 ml/mouse

9.24 ± 0.25

50.20 ± 1.86

Diazepam

1

6.97 ± 0.19***

98.40 ± 3.83***

MECN

50

8.87 ± 0.60

49.00 ± 4.85

MECN

100

7.92 ± 0.27*

69.60 ± 3.12*

MECN

200

7.18 ± 0.28**

92.20 ± 2.44***

  1. Effect of MECN on thiopental sodium induced hypnosis. Values are presented as the Mean ± SEM (n = 5). MECN = Methanolic extract of Crataeva nurvala; *p < 0.05; **p < 0.01; ***p < 0.001 compared with the control group (one-way ANOVA followed by Dunnett’s test)