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Table 4 Effect of MECN on thiopental sodium induced hypnosis

From: The leaves of Crataeva nurvala Buch-Ham. modulate locomotor and anxiety behaviors possibly through GABAergic system

Treatment Dose (mg/kg) Responses
Onset of sleeping Sleeping duration
Control 0.1 ml/mouse 9.24 ± 0.25 50.20 ± 1.86
Diazepam 1 6.97 ± 0.19*** 98.40 ± 3.83***
MECN 50 8.87 ± 0.60 49.00 ± 4.85
MECN 100 7.92 ± 0.27* 69.60 ± 3.12*
MECN 200 7.18 ± 0.28** 92.20 ± 2.44***
  1. Effect of MECN on thiopental sodium induced hypnosis. Values are presented as the Mean ± SEM (n = 5). MECN = Methanolic extract of Crataeva nurvala; *p < 0.05; **p < 0.01; ***p < 0.001 compared with the control group (one-way ANOVA followed by Dunnett’s test)