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Table 1 Effect of MECN on hole cross test

From: The leaves of Crataeva nurvala Buch-Ham. modulate locomotor and anxiety behaviors possibly through GABAergic system

Treatment Dose (mg/kg) Number of hole crossed (% of Inhibition)
Pretreatment 30 min 60 min 90 min 120 min
Control 0.1 ml/mouse 23.40 ± 1.21 18.60 ± 1.44 18.20 ± 1.36 17.00 ± 1.22 15.60 ± 1.08
Diazepam 1 21.40 ± 2.32 6.20 ± 1.07*** (66.67) 3.80 ± 0.58*** (79.12) 2.60 ± 0.51*** (84.71) 1.40 ± 0.24*** (91.03)
MECN 50 22.80 ± 1.28 15.40 ± 0.93 (17.20) 11.80 ± 0.73*** (35.16) 7.80 ± 0.86*** (54.12) 6.00 ± 0.71*** (61.54)
MECN 100 20.60 ± 1.86 10.60 ± 0.75*** (43.01) 9.00 ± 0.71*** (50.55) 4.60 ± 0.93*** (72.94) 3.80 ± 0.86*** (75.64)
MECN 200 21.20 ± 1.85 8.00 ± 0.71*** (56.99) 5.20 ± 0.73*** (71.43) 2.40 ± 0.51*** (85.88) 1.60 ± 0.24*** (89.74)
  1. Effect of MECN on hole cross test. Values are presented as the Mean ± SEM (n = 5). MECN = Methanolic extract of Crataeva nurvala; ***p < 0.001 compared with the control group (two-way ANOVA followed by Bonferroni’s test)
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