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Table 2 Effect of RA-3 on serum antioxidants and C-peptide levels of the diabetic animals

From: A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats

Group

GSH

(nmol/mL)

SOD

(Inhibition rate %)

CAT

(Units/mL)

C-peptide

(μg/L)

Non-diabetic control

7.33 ± 0.010

56 ± 0.005

0.12 ± 0.005

0.8 ± 0.010

Diabetic control

4.31 ± 0.150***

29 ± 0.040**

0.05 ± 0.006*

0.5 ± 0.220****

Diabetic + RA-3

6.05 ± 0.130*#

55 ± 0.011#

0.10 ± 0.004#

0.8 ± 1.020####

Diabetic + metformin

6.40 ± 0.140*#

54 ± 0.012#

0.10 ± 0.006#

0.8 ± 0.410####

  1. Results are expressed as the mean ± SEM, n = 5. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, **** p ≤ 0.0001 versus non-diabetic control, # p ≤ 0.05, #### p ≤ 0.0001 versus diabetic control