Table 8 Genotoxicity test of T. diversifolia and T. rotundifolia using Salmonella typhimurium strains TA98 and TA100 in the absence of exogenous metabolic activation
Plant species | Extracting solvent | Dose (μg/plate) | His + revertants plate | |
|---|---|---|---|---|
TA98 | TA100 | |||
T. diversifolia | Acetone | 5 | 27.33 ± 1.33 | 125.00 ± 1.2 |
50 | 54.67 ± 1.20 | 116.33 ± 1.45 | ||
500 | 45.00 ± 2.52 | 136.00 ± 2.0 | ||
DCM | 5 | 50.00 ± 1.15 | 104.33 ± 1.20 | |
50 | 51.33 ± 1.20 | 115.00 ± 2.00 | ||
500 | 75.33 ± 0.33 | 117.3 ± 0.3 | ||
Hot water | 5 | 56.00 ± 3.00 | 117.00 ± 0.00 | |
50 | 62.00 ± 1.73 | 121.33 ± 0.58 | ||
500 | 63.67 ± 2.52 | 132.33 ± 2.52 | ||
T. rotundifolia | Acetone | 5 | 32.00 ± 1.53 | 122.00 ± 1.0 |
50 | 25.00 ± 0.58 | 113.00 ± 1.15 | ||
500 | 43.33 ± 1.67 | 108.67 ± 1.20 | ||
DCM | 5 | 35.33 ± 0.88 | 111.33 ± 1.76 | |
50 | 29.00 ± 2.08 | 119.00 ± 1.2 | ||
500 | 26.67 ± 1.67 | 122.00 ± 1.7 | ||
Hot water | 5 | 45.00 ± 3.06 | 112.33 ± 4.04 | |
50 | 52.00 ± 3.00 | 112.00 ± 1.73 | ||
500 | 59.00 ± 1.15 | 124.33 ± 3.06 | ||
4NQO + ve control |  |  | 212.7 ± 1.9 | 538.7 ± 5.900 |
H2O –ve control |  |  | 61.33 ± 1.45 | 130.00 ± 2.5 |
10% DMSO –ve control |  |  | 57.00 ± 1.15 | 125.7 ± 1.9 |