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Table 7 Selectivity index of fungal strains tested against T. diversifolia and T. rotundifolia solvent extracts

From: A comprehensive study of the potential phytomedicinal use and toxicity of invasive Tithonia species in South Africa

Plant species

Extract

Selectivity index (SI)

A. fumigatus

C. neoformans

C. albicans

48 h

72 h

48 h

72 h

48 h

72 h

T. diversifolia

EtOH

0.0016

0.0032

0.0571

0.0016

0.0016

0.0016

MeOH

0.0032

0.0032

0.0286

0.0032

0.0008

0.0008

DCM

0.0064

0.0032

0.0267

0.0129

0.0016

0.0016

Acetone

0.080

0.0387

0.1714

0.08

0.08

0.0194

Hot water

0.4436

0.4435

1.8333

0.22

0.22

0.22

T. rotundifolia

EtOH

0.426

0.426

3.553

1.666

0.426

0.426

MeOH

0.836

0.414

1.671

0.836

0.207

0.207

DCM

6.253

0.750

13.400*

6.253

13.400*

6.253

Acetone

11.171*

0.626

11.171*

5.213

11.171*

5.213

Hot water

0.336

NA

1.357

0.336

NA

NA

  1. EtOH ethanol, MeOH methanol, DCM dichloromethane, A. fumigatus Aspergillus fumigatus, C. neoformans Cryptococcus neoformans, C. albicans Candida albicans, NA not available
  2. Values written in bold with asterisk are non-toxic extracts on a safe margin and good promising antifungal agent, while those written in bold with no asterisk are extracts with a relatively safe margin
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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