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Table 1 Antibacterial activity of solvent extracts and fractions of T. diversifolia and T. rotundifolia

From: A comprehensive study of the potential phytomedicinal use and toxicity of invasive Tithonia species in South Africa

Plant species

Extract/fraction

MIC (mg/ml)

Ec

Kp

Ef

SD

Pa

Sa

ST

T. diversifolia

Ethanol

1.25

0.62

0.07*

0.31

1.25

0.31

0.62

Methanol

0.62

0.62

0.62

0.62

1.25

0.62

0.15

DCM

0.31

0.15

0.31

0.31

0.31

0.62

0.62

Acetone

0.15

0.15

0.07*

0.31

0.31

0.62

0.31

Hot water

1.25

0.62

2.5

1.25

1.25

0.15

0.62

Hexane

1.25

0.31

0.62

0.62

0.07*

0.62

0.62

Chloroform

1.25

0.62

0.31

1.25

0.07*

0.15

1.25

Butanol

> 2.5

2.5

> 2.5

> 2.5

> 2.5

> 2.5

> 2.5

ETAC

2.5

2.5

0.62

> 2.5

0.15

0.31

2.5

T. rotundifolia

Ethanol

0.31

0.15

0.31

0.62

0.62

0.07*

0.62

Methanol

0.62

0.31

2.5

0.15

0.62

0.62

0.31

DCM

0.62

0.15

0.15

0.15

0.31

0.07*

0.15

Acetone

0.31

0.07*

0.03**

0.31

0.31

0.07*

0.07*

Hot water

0.01**

0.62

0.07*

0.62

1.25

0.31

0.01**

Hexane

2.5

0.62

1.25

1.25

0.62

1.25

1.25

Chloroform

2.5

> 2.5

1.25

> 2.5

0.62

> 2.5

> 2.5

Butanol

> 2.5

> 2.5

> 2.5

> 2.5

> 2.5

> 2.5

> 2.5

ETAC

0.15

1.25

> 2.5

1.25

1.25

0.62

1.25

Gent 2 mg/ml (+ve con.)

 

0.016*

0.50

0.50

0.004**

0.008**

0.008**

0.08**

  1. DCM dichloromethane, ETAC ethyl acetate fraction, Gent gentamicin, +ve positive control, Ec Escherichia coli, Kp Klebsiella pneumonia, Ef Enterococcus faecalis, SD Salmonella Dublin, Pa Pseudomonas aeruginosa, Sa Staphylococcus aureus, ST Salmonella Typhimurium, T. diversifolia Tithonia diversifolia, T. rotundifolia Tithonia rotundifolia
  2. Values written in bold with no asterisk are considered moderate; Values written in bold with one asterisk are considered active; Values written in bold with two asterisks are considered very active; Values greater than 0.1 mg/ml but less than 2.5 mg/ml are considered as weak activity, while values greater than 2.5 are considered not active
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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