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Table 2 Anti-A5-LOX activity of ethanol extracts of medicinal plants

From: In vitro pro-inflammatory enzyme inhibition and anti-oxidant potential of selected Sri Lankan medicinal plants

Plant name A5-LOX Inhibiton (%)* Anti-A5-LOX activity
IC50 (μg mL− 1)
Sphaeranthus indicus 32.45 ± 0.45a 136.69 ± 1.79a
Acronychiapedunculata 17.45 ± 0.94b 294.68 ± 2.23b
Calophyllum innophyllum 67.14 ± 0.51c 74.82 ± 1.35c
Symplocos cochinchinesis 70.12 ± 0.36c 39.01 ± 0.91d
Tinospora cordifolia 12.71 ± 0.71b 393.63 ± 1.74e
Flacourtia indica 89.35 ± 1.24d 22.75 ± 1.94f
Leucus zeylanica 19.37 ± 0.11b 258.03 ± 1.91g
Barathranthus nodiflorus   9.38 ± 0.32e 213.27 ± 1.55h
Diospyros ebenum 34.91 ± 0.84a 143.76 ± 1.03a
Argyreia populifolia 32.89 ± 0.17a 152.41 ± 1.00i
Baicalein 97.64 ± 0.65f 1.76 ± 0.15j
  1. Data represented as mean ± SE (N = 3). *A5-LOX Inhibition at 100 μg/mL. Mean within each column followed by the same letter are not significantly different at p < 0.05