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Table 2 Concentration parameters of the selected plant extracts on PANC-1 cell line sensitivity depending on the extraction method

From: Identification of antitumoral agents against human pancreatic cancer cells from Asteraceae and Lamiaceae plant extracts

   Extraction Method
SFE UAE Commercial
Concentration Parameter   OVM  
Plant extract   Ethanol  
Marjoram IC50 > 100
GI50 > 100
TGI > 100
LC50 > 100
Yarrow IC50 > 100 > 100 >  500
GI50 24,5 ± 0,26 > 100 >  500
TGI 96,4 ± 6,2 69,2 ± 1,1 >  500
LC50 > 100 > 100 >  500
Marigold IC50 43,2 ± 7,9 >  500
GI50 > 100 >  500
TGI 45,9 ± 1,8 >  500
LC50 74,2 ± 6,6 >  500
  1. Data (> 100): not significant activity found at 100 μg/mL concentration; (−): not determined; SFE Supercritical Fluid Extraction, UAE Ultrasound Assisted Extraction, OVM Original Vegetable Matrix
  2. Data are presented as IC50 (μg/mL) (concentration needed for 50% inhibition of cell proliferation), GI50 (μg/mL) (concentration needed for 50% growth inhibition), TGI (μg/mL) (concentration needed for total growth inhibition) and LC50 (μg/mL) (concentration needed for 50% cell death) after 48 h’ treatment as mean ± SEM of at least three independent experiments each performed in quadruplicate