| | |
Extraction Method
|
|---|
|
SFE
|
UAE
|
Commercial
|
|---|
|
Concentration Parameter
| |
OVM
| |
|---|
|
Plant extract
| |
Ethanol
| |
|---|
|
Marjoram
|
IC50
|
> 100
|
–
|
–
|
|
GI50
|
> 100
|
–
|
–
|
|
TGI
|
> 100
|
–
|
–
|
|
LC50
|
> 100
|
–
|
–
|
|
Yarrow
|
IC50
|
> 100
|
> 100
|
> 500
|
|
GI50
|
24,5 ± 0,26
|
> 100
|
> 500
|
|
TGI
|
96,4 ± 6,2
|
69,2 ± 1,1
|
> 500
|
|
LC50
|
> 100
|
> 100
|
> 500
|
|
Marigold
|
IC50
|
43,2 ± 7,9
|
–
|
> 500
|
|
GI50
|
> 100
|
–
|
> 500
|
|
TGI
|
45,9 ± 1,8
|
–
|
> 500
|
|
LC50
|
74,2 ± 6,6
|
–
|
> 500
|
- Data (> 100): not significant activity found at 100 μg/mL concentration; (−): not determined; SFE Supercritical Fluid Extraction, UAE Ultrasound Assisted Extraction, OVM Original Vegetable Matrix
- Data are presented as IC50 (μg/mL) (concentration needed for 50% inhibition of cell proliferation), GI50 (μg/mL) (concentration needed for 50% growth inhibition), TGI (μg/mL) (concentration needed for total growth inhibition) and LC50 (μg/mL) (concentration needed for 50% cell death) after 48 h’ treatment as mean ± SEM of at least three independent experiments each performed in quadruplicate
