Skip to main content

Table 2 Concentration parameters of the selected plant extracts on PANC-1 cell line sensitivity depending on the extraction method

From: Identification of antitumoral agents against human pancreatic cancer cells from Asteraceae and Lamiaceae plant extracts

  

Extraction Method

SFE

UAE

Commercial

Concentration Parameter

 

OVM

 

Plant extract

 

Ethanol

 

Marjoram

IC50

> 100

–

–

GI50

> 100

–

–

TGI

> 100

–

–

LC50

> 100

–

–

Yarrow

IC50

> 100

> 100

>  500

GI50

24,5 ± 0,26

> 100

>  500

TGI

96,4 ± 6,2

69,2 ± 1,1

>  500

LC50

> 100

> 100

>  500

Marigold

IC50

43,2 ± 7,9

–

>  500

GI50

> 100

–

>  500

TGI

45,9 ± 1,8

–

>  500

LC50

74,2 ± 6,6

–

>  500

  1. Data (> 100): not significant activity found at 100 μg/mL concentration; (−): not determined; SFE Supercritical Fluid Extraction, UAE Ultrasound Assisted Extraction, OVM Original Vegetable Matrix
  2. Data are presented as IC50 (μg/mL) (concentration needed for 50% inhibition of cell proliferation), GI50 (μg/mL) (concentration needed for 50% growth inhibition), TGI (μg/mL) (concentration needed for total growth inhibition) and LC50 (μg/mL) (concentration needed for 50% cell death) after 48 h’ treatment as mean ± SEM of at least three independent experiments each performed in quadruplicate
Back to article page

BMC Complementary Medicine and Therapies

ISSN: 2662-7671

Contact us