|
Groups
|
Body weight (g)
|
Body weight variation (%)
|
Liver weight (g/100 g BW)
|
Intestine weight (g/100 g BW)
|
Spleen weight (g/100 g BW)
|
|---|
|
Pre-infection / Pre-treatment
|
Post-infection / Post - treatment
|
|---|
|
UIC
|
26.03 ± 0.86
|
35.70 ± 0.99$$$
|
38.28 ± 4.83 (27.66–48.91)
|
4.65 ± 0.25
|
4.09 ± 0.11
|
0.26 ± 0.02
|
|
IC
|
24.91 ± 0.88
|
30.39 ± 0.97$$$
|
22.94 ± 3.92 (14.31–31.56)*
|
9.04 ± 0.31***
|
8.81 ± 0.32***
|
1.23 ± 0.14***
|
|
PZQ
|
24.43 ± 0.25
|
31.40 ± 0.46$$$
|
28.60 ± 1.77 (24.78–32.42)
|
4.85 ± 0.05###
|
8.39 ± 0.29***
|
0.52 ± 0.03###
|
|
SpAE 200
|
23.76 ± 0.51
|
29.86 ± 0.66$$$
|
26.49 ± 3.09 (19.70–33.28)
|
7.77 ± 0.18***, ###, £££
|
7.61 ± 0.31***, #
|
0.93 ± 0.11***, #, ££
|
- UIC Uninfected-untreated mice, IC Infected-untreated mice, PZQ Infected mice treated with praziquantel, SpAE 200 Infected mice treated with Sida pilosa aqueous extract at 200 mg/kg
- Data are expressed as mean ± SEM (n = 6). Student t test was used to compare values at pre-infection / pre-treatment and values at post-infection / post-treatment: $$$p < 0.001: values are significantly different from those at pre-infection / pre-treatment. ANOVA followed by Newman-Keuls multiple comparison test was also used for statistical analysis. *p < 0.05, ***p < 0.001: values are significantly different from those of uninfected-untreated mice (group UIC). #p < 0.05, ###p < 0.001: values are significantly different from those of infected-untreated mice (group IC). ££p < 0.01; £££p < 0.001: values are significantly different from those of infected mice treated with praziquantel (group PZQ). Values in brackets represent the lower and upper 95% confidence intervals
