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Table 1 Effect of oral treatment of Sida pilosa aqueous extract on the body weight and organs weights of Schistosoma mansoni-infected mice

From: Efficacy of Sida pilosa Retz aqueous extract against Schistosoma mansoni – induced granulomatous inflammation in the liver and the intestine of mice: histomorphometry and gastrointestinal motility evaluation

Groups Body weight (g) Body weight variation (%) Liver weight (g/100 g BW) Intestine weight (g/100 g BW) Spleen weight (g/100 g BW)
Pre-infection / Pre-treatment Post-infection / Post - treatment
UIC 26.03 ± 0.86 35.70 ± 0.99$$$ 38.28 ± 4.83 (27.66–48.91) 4.65 ± 0.25 4.09 ± 0.11 0.26 ± 0.02
IC 24.91 ± 0.88 30.39 ± 0.97$$$ 22.94 ± 3.92 (14.31–31.56)* 9.04 ± 0.31*** 8.81 ± 0.32*** 1.23 ± 0.14***
PZQ 24.43 ± 0.25 31.40 ± 0.46$$$ 28.60 ± 1.77 (24.78–32.42) 4.85 ± 0.05### 8.39 ± 0.29*** 0.52 ± 0.03###
SpAE 200 23.76 ± 0.51 29.86 ± 0.66$$$ 26.49 ± 3.09 (19.70–33.28) 7.77 ± 0.18***, ###, £££ 7.61 ± 0.31***, # 0.93 ± 0.11***, #, ££
  1. UIC Uninfected-untreated mice, IC Infected-untreated mice, PZQ Infected mice treated with praziquantel, SpAE 200 Infected mice treated with Sida pilosa aqueous extract at 200 mg/kg
  2. Data are expressed as mean ± SEM (n = 6). Student t test was used to compare values at pre-infection / pre-treatment and values at post-infection / post-treatment: $$$p < 0.001: values are significantly different from those at pre-infection / pre-treatment. ANOVA followed by Newman-Keuls multiple comparison test was also used for statistical analysis. *p < 0.05, ***p < 0.001: values are significantly different from those of uninfected-untreated mice (group UIC). #p < 0.05, ###p < 0.001: values are significantly different from those of infected-untreated mice (group IC). ££p < 0.01; £££p < 0.001: values are significantly different from those of infected mice treated with praziquantel (group PZQ). Values in brackets represent the lower and upper 95% confidence intervals