The protective effect of Er-Xian decoction against myocardial injury in menopausal rat model

Table 1 Effect of EXD on ventricular action potentials

	RMP (mV)	Vmax (V/s)	APA (mV)	APD₅₀ (ms)	APD₉₀ (ms)
SHAM	−65.04 ± 6.01	10.05 ± 3.72	85.45 ± 17.04	50.32 ± 1.85	114.78 ± 16.03
OVX	−68.05 ± 4.51	10.98 ± 4.78	90.35 ± 10.12	34.75 ± 4.42^**	89.14 ± 7.09^*
E2	−60.88 ± 8.07	7.32 ± 2.24	82.59 ± 10.27	43.55 ± 3.07^#	90.58 ± 11.87
EXD	−66.14 ± 9.20	8.08 ± 3.22	88.97 ± 13.54	44.00 ± 4.01^#	95.59 ± 17.18

SHAM: sham-operated, OVX: ovariectomized, E2: 17β-estradiol, EXD: Er-Xian decoction, RMP: resting membrane potential, Vmax: maximal rate of depolarization, APA: AP amplitude, APD₅₀: AP duration at 50%, APD₉₀: AP duration at 90%. Values are presented as the means ± SD (n = 9 in each group). ^* P < 0.05 versus SHAM group; ^** P < 0.01 versus SHAM group; ^# P < 0.05 versus OVX group

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