Fig. 8

Alteration in the gene expression profile of IL-10, IL-12 P40 and IL-6 before and after tumor lysate pulsing of dendritic cells. The data show the fold change between loaded /unloaded DCs. The data were normalized to GAPDH mRNA expression level. #P < 0.05 represents the significant difference from LPS -DCs. *P < 0.05, **P < 0.01, and ***P < 0.001 represent significance to unloaded DCs. The data are given in mean value ± SEM of three experiments comprising three different healthy donors. iDCs, immature dendritic cells; TLY, tumor lysate; LPS, Lipopolysaccharide