Induction of programmed cell death in Trypanosoma cruzi by Lippia alba essential oils and their major and synergistic terpenes (citral, limonene and caryophyllene oxide)

Table 2 Peak assignment for GC-MS profiles of essential oils extracted by microwave-assisted hydrodistillation (MWHD) from Lippia alba Carvone (A) and Citral (B) chemotypes plants growing in Bucaramanga (Colombia)

Peak	Compound	LRI		Relative Quantity, %
Peak	Compound	DB-5MS^a	DB-WAX^b	Carvone (A)	Citral (B)
1	6-Methyl-5-hepten-2-one	986	1241	–	3.3
2	β-Myrcene	991	1064	0.8	–
3	Limonene	1034	1105	29.1	6.6
4	trans-β-Ocimene	1047	1153	0.7	0.2
5	Linalool	1100	1453	0.6	1.9
6	Citronellal	1154	1381	–	1.1
7	Borneol	1181	1613	0.8	–
8	cis-Dihydrocarvone	1203	1517	0.2	–
9	trans-Dihydrocarvone	1211	1537	0.2	–
10	Nerol	1231	1708	–	0.8
11	Neral	1248	1589	–	21.5
12	Geraniol	1252	1755	–	5.6
13	Carvone	1258	1653	35.0	–
14	Piperitone	1264	1641	2.4	–
15	Geranial	1275	1643	–	28.7
16	Piperitenone	1349	1842	4.0	–
17	Geranyl Acetate	1379	1662	–	1.5
18	β-Bourboneno	1396	1428	1.2	–
19	β-Elemene	1397	1496	1.0	3.0
20	trans-β-Caryophyllene	1436	1506	0.2	12.1
21	β-Gurjunene	1444	1447	0.2	–
22	α-Guaiene	1447	1498	–	1.8
23	trans-β-Farnesene	1456	1570	0.7	–
24	α-Humulene	1471	1580	0.1	2.7
25	γ-Gurjunene	1475	1587	0.4	–
26	Germacrene D	1486	1552	0.1	2.6
27	Bicyclosesquiphellandrene	1496	1624	8.2	–
28	Bicyclogermacrene	1509	1608	0.5	–
29	α-Bulnesene	1515	1627	–	1.4
30	Cubebol	1528	1855	0.5	–
31	Germacrene-4-ol	1591	1967	0.6	–
32	Caryophyllene Oxide	1600	1909	–	2.3

ISSN: 2662-7671