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Table 2 Antibacterial activities of crude ethanolic extract of S. asper leaves and its fractions against a range of microorganisms determined by the broth microdilution method

From: Acid-base fractions separated from Streblus asper leaf ethanolic extract exhibited antibacterial, antioxidant, anti-acetylcholinesterase, and neuroprotective activities

Microorganisms Minimum inhibitory concentration (MIC) in μg/mL
Crude extract Neutral fraction Acidic fraction Basic fraction
Gram-positive bacteria
Staphylococcus aureus (ATCC25923) 1000 1000 125 1000
Bacillus subtilis (SU5) 1000 250 125 500
Gram-negative bacteria
Escherichia coli (MG1655) > 1000 > 1000 > 1000 > 1000
Pseudomonas aeruginosa (PA14) > 1000 > 1000 > 1000 > 1000
  1. MIC values are the lowest concentrations at which at least 95% bacterial growth reduction
  2. The tested concentration of samples ranged from 125 to 1000 μg/mL