Fig. 1

Effects of corylin on the cell viability and the production of NO by LPS-activated BV2 cells. BV2 cells were pre-treated with various doses of corylin for 1 h, and then treated with LPS (1 μg/mL) for 24 h. a The survival rate of BV2 cells was measured by MTT assay. b The production of NO in the cell culture supernatant was detected by Griess reaction. c The expression of COX-2 and iNOS was examined by Western blot. Blots are representative blots. The relative ratio of (d) iNOS /β-actin and (e) COX-2/β-actin are shown. Data represent mean ± SD of three independent experiments (*: p < 0.05; **: p < 0.01; ***: p < 0.001 vs. LPS alone)