Fig. 4

a Effects of verapamil or MK801 on CBNPs-induced PKC-α activation in A549 cells. b Effects of verapamil, MK801, or Gö6976 on CBNP-induced Nox2 activation in A549 cells. c Effects of DPI or apocynin on CBNPs-induced PKC-α activation in A549 cells. Cell were pretreated with verapamil, MK801, Gö69761, DPI, or apocynin for 1 h, respectively, and then treated with CBNPs (25 μg/mL) for 1 h or 24 h for determination of PKC-α and Nox, respectively. Bars represent the mean ± S.E.M. from six independent experiments. ^##P < 0.01 vs. control group (without any treatment). ^**P < 0.01 vs. CBNPs (25 μg/mL) group