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Fig. 9 | BMC Complementary and Alternative Medicine

Fig. 9

From: Water extract of Clinacanthus nutans leaves exhibits in vitro, ex vivo and in vivo anti-angiogenic activities in endothelial cell via suppression of cell proliferation

Fig. 9

Effect of C. nutans water extract on VEGF-induced angiogenesis. Suramin at a dose of 1000 μg/disc was used as a positive control. a C. nutans extract inhibited vessel sprouting in CAM model induced by VEGF. Representative results were shown. b The histogram shows the number of blood vessels contacting the discs. The values presented are the mean ± SEM of three independent experiments. *p < 0.05 were considered significant when compared to normal control (N); #p < 0.05 were considered significant when compared to VEGF alone group

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