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Table 2 Group names and definition of the conditions used to treat the various experimental groups of cells or animals. In vivo eletrophysiological and histopathological experimentsa

From: Dendrobium nobile Lindley and its bibenzyl component moscatilin are able to protect retinal cells from ischemia/hypoxia by dowregulating placental growth factor and upregulating Norrie disease protein

Group names Definition of conditions of animals that received
i. Sham (n = 12; control) sham procedure
ii. Vehicle+I/R (n = 12) Pre-ischemic treatment with vehicle followed by I/R
iii. DNL0.5 + I/R (n = 12) Pre-ischemic treatment with DNL0.5 followed by I/R
iv. DNL1.0 + I/R (n = 12) Pre-ischemic treatment with DNL1.0 followed by I/R
v. I/R + Vehicle (n = 10) I/R followed by post-ischemic treatment with vehicle
vi. I/R + DNL1.0 (n = 10) I/R followed by post-ischemic treatment with DNL1.0
  1. aThese animals were evaluated by ERG and sacrificed for histopathological studies, namely cresyl violet, ChAT and vimentin/GFAP labelings. Subtotally, 68 animals were used. Pre−/post-ischemia oral gavage of 0.5 g/kg/day (DNL0.5 + I/R), 1.0 g/kg/day of DNL (DNL1.0 + I/R; I/R + DNL1.0), or the same volume of vehicle was given (Vehicle+I/R; I/R + Vehicle). Abbreviations: ChAT choline acetyltransferase, GFAP glial fibrillary acidic protein